Skovenborg, E., Grønbæk, M., Ellison, R.C. "Benefits and hazards of alcohol-the J-shaped curve and public health". Drugs and Alcohol Today 2021;21:54-69. The purpose of this paper is a review of updated evidence of a J-shaped association between alcohol consumption and the risk of coronary heart disease (CHD) and all-cause mortality in relation to public health issues to create a basis for sensible individual health deliberations.
Grønbæk, M., Ellison, R.C., Skovenborg, E. "The J-shaped curve-conceptual and methodological challenges". Drugs and Alcohol Today 2021;21:70-83. A number of methodological problems are common in observational research in general, and some of the methodological problems suggested for the J-shaped alcohol-CHD-associations are discussed.
Ellison, R.C., Grønbæk, M., Skovenborg, E. "Using Mendelian randomization to evaluate the effects of alcohol consumption on the risk of coronary heart disease”. Drugs and Alcohol Today 2021;21:84-95.The paper present a review of methodology for MR and describes its early application to judging health effects of alcohol, current uses and a recommended approach of combining MR results with those from observational and experimental studies.